Article ID: 937542 - View products that this article applies to.
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Microsoft Forefront Security for Exchange Server notifications stop working if you change the Exchange Pickup folder path.
To resolve this problem, install Hotfix Rollup 1 for Forefront Security for Exchange Server.
For more information, click the following article number to view the article in the Microsoft Knowledge Base:
(http://support.microsoft.com/kb/936831/ )Description of Hotfix Rollup 1 for Microsoft Forefront Security for Exchange Server
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.